A Serum NTx level is used to aid in predicting skeletal response (bone mineral density) to

antiresorptive therapy and in monitoring bone resorption changes following initiation of

antiresorptive therapy. Prior to initiating antiresorptive therapy, a serum NTx level is used to

determine the probability for a decrease in bone mineral density (BMD) after one year in

postmenopausal women treated with hormonal antiresorptive therapy relative to those treated

with calcium supplementation.

The measurement range of Osteomark NTx Serum is 3.2 to 40.0 nM Bone Collagen Equivalents

(BCE).